Introduction:

With the inauguration of government medical college, Nagpur in 1947 the department of pharmacology was established. Dr N K Sinha was 1st Head of Department. Till then total 17 professors guided the department as a Head & at present Dr V M Motghare is the Head of Department since 2014. The department is situated on the second floor of college building which include the offices of main department, institutional ethics committee, pharmacovigilance committee, drug store and the undergraduate teaching section which include museum, library and laboratories for experimental pharmacology, pharmacy & clinical pharmacology. The department has instituted innovation in teaching like introduction of computer added teaching methods, p drug concept and case based discussion etc. along with age old experimental pharmacology. Various research activities are also going on in the department.

Faculty Pharmacology

Faculty Attendence

Publication/Presentation

Research publications since last three years in indexed journals dated July 2018

Sr

Name of teachers

Title of research article

Authors

1

Dr.V .M. Motghare

1.Impact of educational intervention on knowledge and attitude about rational use of medicine among doctors doing internship. Indian journal of Pharmacy and Pharmacology, January-March 2017;4(1):62-65.

Bajait CS, Motghare VM, Pimpalkhute SA, Dakhale GN, Jire AS

 

 

2.A retrospective study to determine adverse effects of anti-retroviral agents in tertiary care hospital in Central India. Indian journal of Pharmacy and Pharmacology. 2017;4(3):147-152

VS Sharma, VM Motghare, GN Dakhale, SA Pimpalkhate, CS Bajait.

 

 

3.Study of prescription pattern and adverse drug reaction monitoring  in patients of oral cavity malignancies attending radiotherapy  department at a tertiary care teaching institute. Indian journal of Pharmacy and Pharmacology, January-March 2017;4(1):62-65.

Motghare VM, Dhargave NH, Bajait CS, Mahobia V,Diwan AK..

 

 

4.Prescription pattern and adverse drug reaction profile of drugs prescribed in dermatology out patient department at a tertiary care teaching hospital. Indian journal of Pharmacy and Pharmacology, October-December 2016;3(4):173-177.

Motghare VM, Bajait CS, Turankar A, Sontakke SD, Chavan S.

 

 

5.Prescription pattern and adverse drug reaction profile of drugs prescribed with focus on NSAIDs for orthopaedic indications at a tertiary care teaching hospital. Indian journal of Pharmacy and Pharmacology, October-December 2016;3(4):178-181.

Motghare VM, Bajait CS, Turankar A, Pimpalkhute SA, Dholpure M

2

Dr.G.N. Dakhale

1.Comparison of efficacy, safety and cost effectiveness of Rupatidine, Olapatidine in patients of allergic rhinitis, A prospective randomized, double blind , parallel group study. Jornal of pharmacology & Pharmacotherapeutics. 2016;7(4):171-76.

Dakhale GN, Tathod Y, Patel S, Pimpalkhute SA, Raghute L, Khamkar A.

 

 

2.Comparison of efficacy, safety and cost effectiveness of Rupatidine and Olapatidine in patients of chronic spontaneous urticaria: A randomized double blind,comparative , parallel group trial. Indian journal of Dermatology. 2016;61(1):63-69.

Dakhale GN, Wankhede S, Mahatme M, Hiware S, Mishra D, Dudhagaonkar S.

 

 

3.Clinical efficacy and Safety of Telmisartan versus Losartan and their effect on lipid profile. A Randomized, double blind, 12 week trial.IJPR2015;5(4):80-85.

Dakhale Gn, Salve A, Hardas M, Mahatme M, Hiware S, Shinde A.

3

Dr. S. Mahakalkar

1.N-acetyl cysteine as an add on to directly observed therapy short 1 therapy in fresh pulmonary TB patients. A randomized placebo controlled, double blinded study. 2017;117(8):132-38.

Mahakalkar S, Nagrare D, Gaur S, Urade C.Murar B, Turankar A.

 

 

2.Comparison of effect of fluvoxamine or risperidone to clozapine in chronic partially responsive schizophrenic patients on clinical response, QTc interval and lipid profile.. International journal of Pharmacological research.2016; 6(7):231-37.

Mahakalkar S, Patil ,Urade C, Bajait C

4

Dr Smita Sontakke

1.Medication prescribing pattern in pediatric diarrhea with focus on zinc supplements. International journal of Nutrition, Pharmacology, Neurological diseases. 2016;42:152-56.

 

 

 

2.Complementary and alternative medicine use in children with haematological disorders. World J Pharm Sci 2016;4910):43-49.

Sontakke SD, Sinde V, Motghare VM, Pimpalkhute SA, Bajait CS, Jaiswal KM

 

 

3.Evaluation of parental perception about self medication and other medicine use practices in children. Europeon journal of pharmaceutical and medical research. 2015;2(7):179-85.

Sontakke SD, Magdum A, Jaiswal KM, Bajait CS, Pimpalkhute SA, Dakhale GN.

 

 

4.Evaluation of adherence to therapy in patients of Type II diabetes mellitus. Journal of Young Pharmacist. 2015;7(4):462-69.

Sontakke SD, Jadhav M, Pimpalkhute SA, Jaiswal KM, Bajait CS.

5

Dr. A.V. Turankar

1. Effect of power posing on Basic cardiovascular parameters: A short term pilot study; Indian Journal of Basic and Applied Medical Research; December 2016: Vol.-6, Issue- 1, P. 137-142.

 

Dr Avinash Vikram Turankar, Dr Rushikesh Prabhakar Deshpande, Yogesh Ajmera, Dr Latesh Raghute

 

 

2. Effect of levofloxacin on psychomotor performance test and blood sugar level in healthy human volunteers , Medpulse International Journal ofpharmacology, March 2017, 1( 3), P. 01 to 05.

 

Amruta Dawari , Turankar Avinash,Bankar Mangesh

 

 

3. Comparative study of knowledge, attitude and practices of pharmacovigilance programme between clinicians and nurses in tertiary care Teaching Hospital of Central India, Indian Journal of Pharmacy and Pharmacology, April June 2017, 4( 2), P. 95 to 100.

Chetan urade, AvinashTurankar, Vinay Bajaj, Vijay motghare, Ganesh Dakhale

 

 

4. Effect of ciprofloxacin a fluoroquinolone drug on psychomotor performance tests  and blood sugar levels in healthy humans., published in medpulse international journal of pharmacology ,March 2017, 1 (3 ), P. 33 - 37.

Amruta Dawri, Turankar  AV, Bankar M A

 

 

6. Influence of digit ratio digit ratio 2D 4D on reaction time and athletic sprint performance , a short-term term pilot study ,original research article, medpulse International Journal of physiology: Feb 2018,5(2), P. 17-21.

MK Tambe AV Turankar,  S Lingawar et all

6

Dr Mrunalini Kalikar

1.Efficacy and tolerability of olmesartan, telmisartan and losartan in patients of stage I hypertension: A randomised open label study. J pharmacology and pharmacotherapeutics.Oct 2017; 8 (3) :106-11

M.kalikar,K.Nivangune,G.Dakhle,C.Bajait, S.Sontakke.V.Motghare,R.Budania.

 

 

2.Evaluation of knowledge, attitude and practice about antihypertensive drug use in hypertensive patients in a tertiary care teaching hospital. World J Pharm Sci 2016;4(9):385-388.

Pimpalkhute SA, Bajait CS, Dakhale GN,   Jaiswal KM, Sontakke SD, Niwangune KS

7

Dr Chaitali Chindhalore

1. Impact of educational intervention on knowledge and attitude about rational use of medicine among doctors doing internship. Indian journal of Pharmacy and Pharmacology, January-March 2017;4(1):62-65.

Bajait CS, Motghare VM, Pimpalkhute SA, Dakhale GN, Jire AS

 

 

2.Vitamin D status in chronic kidney disease: an observational study. World journal of Pharmacy and Pharmaceutical Sciences. 2016;5(1):1376-82.

Bajait CS, Dakhale GN,. Pimpalkhute SA,Tathod Y, Raghute L.

8

Dr Harshal Pise

1. Awareness and impact of educational intervention regarding kangaroo mothercare among pediatricians of Marathwada region of Maharashtra

Manish Tiwari1, Harshal N Pise2

 

 

2. Clinico-epidemiological profile of acute poisoning cases admitted in a rural tertiary care hospital of Maharashtra

Vinod Limbanath Vedpathak, Harshal Nutanrao Pise, Pramod Kharade

 

 

3. Drug prescribing and dispensing pattern in pediatrics

outpatient clinic of a rural tertiary-care teaching hospital

Harshal N Pise, Sudhir L Padwal, Rakesh R Jadhav, Vinod S Deshmukh, Asha D Jadhav, Atul M Kolhe

 

 

4. Investigation of analgesic activity of Xanthine Oxidase inhibitor Allopurinol: An experimental study

Pise HN, Padwal SL, Motghare VM, Deshmukh VS, Jaykare SC, Jadhav SS

9

Dr Vishal Ubale

Evaluation of antidepressant activity of tramadol in mice - An experimental study.

 International Journal of Basic & Clinical Pharmacology | May-June 2015 | Vol 4 | Issue 3 Page 463-68.

Vishal M. Ubale, Jugalkishore B. Jaju, Punam A. Gosavi, Ganesh R. Pawar, Shrikant C. Dharmadhikari, Sonal M. Parekar

10

Dr Punam Gosavi

Study of evaluation of anti-inflammatory activity of macrolide antibiotics in  rats: an experimental study.

International journal of basic & clinical pharmacology.  (September-October, 2015/Vol.4/Issue 5, 987-992)

Gosavi PA,  Jaju JB,  Ubale VM, Pawar GR,  Dharmadhikari SC

11

Dr Nishikant Mankar

1.Efficacy of alternate day versus daily atorvastatin in reduction of low density lipoprotein cholesterol: a prospective, randomized, open labelled, parallel group study. Int J Basic Clin Pharmacol. 2016 Aug;5(4):1421-1424

Mankar NN, Zad VR,Vakharia MP.

 

 

2.Knowledge, attitude and practices towards ayurvedic medicine use among second year mbbs students.

 Journal of Evolution of Medical and Dental Sciences 2015; Vol. 4, Issue 02, January 05; Page: 223-227

 

 Mankar NN, Zad VR , Agharia M. Sawant S , Bansode A.

12

Dr Bhushan Dudhe

1.Knowledge, Attitude and Practice of Clinician Regarding Reporting of Adverse Drug Reaction (ADR) in Dr. Panjabrao Deshmukh Memorial Medical College, Amravati. World J Pharm Sci 2018; 6(2): 62-69

Dudhe B., Bhore A.

 

 

2.Effect of flupirtine on seizure activity and its interactions with antiepileptic drugs in rats. Int. J. Adv. Res. 5(7), 1824-1828

Dudhe BG,  Badwaik RT, Bhore AS.

 

 

3.Anticonvulsant Action of Flupirtine and its Interaction with Antiepileptic Drugs in Rats. J Cont Med A Dent .2016 Volume 4 Issue 2

Dudhe BG, Bhore AS

13

Dr Ulhas Ghotkar

 Identification and assessment of adverse drug reactions in patients with bronchial asthma receiving anti-asthmatic medication. National Journal of Medical and Dental Research, July-Sep. 2016: Volume-4, Issue-4, Page 247-251

Ghotkar UM ,  Khandelwal PN. Kulkarni M,  Thawani V, Doifode SM, Sayad A Maaz.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Paper Presentations by the Teachers and PG Students From Department of Pharmacology, GMC, Nagpur

Dr. G.N. Dakhale, Prof.

  • 44 th National conference of IJP at Manipal in December 2011. Prescribing pattern of medicine in paediatric patients suffering from acute diarrhoea in IGGMC, Nagpur.
  • 44th National conference of IJP at Manipal in December 2011. Comparative double blind study of safety and efficacy of oral Rupatidine and Cetirizine in patients of chronic idiopathic urticaria.
  • Presented paper in Staff Research Society at IGGMC, Nagpur on 13.03.2012 on Medical store management
  • Compete for Suryakumari Award in 45th National conference of IPS at Nagpur in January 2013. Supplementation of vitamin C reduces blood glucose and improves glycosylated hemoglobin in type 2 DM: a randomized double blind study. Advances in paharmacological sciences, vol 1, 2011.

Dr. Turankar , Associate Prof.

A research paper entitled “Comparitive evaluation of serum vitamin D levels in healthy volunteers and patients of rheumatoid arthritis. “ authored by Dr Satyajit Jagtap , Dr A.V. Turankar , dr Mangesh Bankar, Dr Kavita Jaiswal , Dr Chetan Urade , Dr Suresh Pawar (presenter), Dr Mayur Jadhav, Dr Ayudh Magdum in Third international and sixth national Annual conference of Indian Society for Rational Pharmacotherapeutics ISRPTCON -2014 at Dept of Pharmacology and clinical pharmacology,JIPMER Puducherry

Dr. Smita Sontakke, Associate Prof.

“Prescription audit of antidiabetic medicines: a comparison between government and private set-up” at 45th annual conference of Indian pharmacological society from 5 to 7 jan 2013 at Nagpur

Dr. Mrunalini Kalikar, Associate Prof.

In 45th annual conference of Indian pharmacological society on 5 to 7 jan 2013- Evaluation of awareness about pharmacovigilance and adverse drug reaction monitoring in resident doctors of a tertiary care teaching hospital

Dr. Swarnank Parmar, Senior resident

“Drug Utilization study in Special Neonatal Care Unit of a teaching tertiary care hospital” International & 6th National Annual conference of ISRPT – JIPMER, Puducherry 21/11/2014 & 22/11/2014

 

Research

Ongoing Research Projects in the Department of Pharmacology

Dr. Turankar, Associate Prof.
1. ICMR short term student ship 2015 with the research topic “effect of power posing on basic cardiovascular parameters : A short term pilot study” reference ID 2015-01792 : name of the MBBS 2nd year student Mr Yogesh Ajmera.
2. Completed PG thesis :Title” to evaluate and compare effect of Ecitalopram amitriptyline and Mirtazapine on psychomotor performance and cognitive function in patients of depression” the name of the post graduate student is Dr Suresh Pawar .

Dr. Mrunalini Kalikar , Associate Prof.
1. Comparative evaluation of efficacy and safety of oral diclofenac versus transdermal diclofenac patch in patients suffering from chronic musculoskeletal pain: a randomized, open label trial.
2. Adherence to treatment of tuberculosis and AIDS in patients with TB/HIV co-infection on concomitant treatment .
3. Evaluation of knowledge, attitude and practice of rational use of medicine among interns in a tertiary care teaching hospital .

Dr. Chaitali Bajiat, Assistant Prof.
1. Estimation of serum level of vit D3 in chronic kidney disease patients.
2. Adherence to treatment of tuberculosis and AIDS in patients with HIV-TB co-infection.
3. Evaluation of knowledge , attitude and practice of rational use of medicine among interns in a tertiary care teaching hospital

Dr. Chetan S. Urade, Assistant Prof.
Comparative study of knowledge, attitude and practices of pharmacovigilance programme between clinicians and nurses in tertiary care teaching hospital of central India

Dr. Swarnank Parmar JR 3
“Drug Utilization study in Special Neonatal Care Unit of a teaching tertiary care hospital in central India”

Dr Ajita Khamkar JR 3
“ Drug utilization study in geriatric patients attending various OPDs at tertiary care teaching hospital in central India”

Dr Shinde Viraj JR 3
“ Comparative evaluation of efficacy and safety of oral diclofenac versus transdermal diclofenac patch in patients suffering from chronic musculoskeletal pain : A randomized. open label trial”

Dr Latesh Raghute JR 3
“Adverse drug reaction profile at Radiotherapy, Paediatrics and Ear, Nose and Throat department of a tertiary care teaching hospital : A descriptive cross sectional study”.

Workshop/CME/Conference

Institutional Ethics Committee (IEC), Department of Pharmacology, Government Medical College (GMC), Nagpur successfully organized training workshops on ‘Good Clinical Practice (GCP) and Schedule Y Update’ on 24th July 2018 and 28th July 2018. These were 13th and 14th workshops in tandem. Approximately 50 participants were present in each workshop. The essence of the workshops were the interactive sessions.

The participants were enlightened on various topics like Responsibilities of Investigator, Sponsor and Monitor, Principles of ICH-GCP and Indian GCP, Ethical issues in biomedical research, Role of Ethics Committee members in protocol review, Serious Adverse Events & Compensation, Indian regulatory guidelines and update on Schedule Y. Dr. V. M. Motghare, Professor and Head, Department of Pharmacology, Dr. G. N. Dakhale, Professor and Member Secretary of IEC, GMC, Nagpur, Dr. A. V. Turankar, Associate Professor and Dr. M. V. Kalikar, Associate Professor were available as the faculty. Dr. A. K. Niswade, Dean GMC Nagpur, was present as the chief guest for the valedictory function on 24th July 2018, who shared his experience and thoughts about the workshop and clinical research.

Awards & Achievements

Awards & Achievements 2013 – 2016

  • There are total 68 research publications in various national and International indexed journals from department in last 3 years.
  • In last 3 years, 5 workshops on ‘GCP & ethics in biomedical research ‘had been conducted by Institutional Ethics Committee, Dept of Pharmacology.
  • Department had conducted two workshop on ‘Basic Biostatistics in medical research’ in last 3 years.
  • Department had completed two projects sponsored by ICMR entitled ‘ Effect of power posing on basic cardiovascular parameters in healthy volunteers: a short term pilot study’ which was presented at MEDICON 2016 10th International undergraduate medical student research conference of informer hosted by Era’s Lucknow medical college and hospital Lucknow on 15th july 2016 under the guidance of Dr A V Turankar and ‘Medication prescribing pattern in paediatric diarrhoea with focus on zinc supplements’ under the guidance of Dr Sontakke.
  • Department has established Therapeutic drug monitoring (TDM) unit with establishment of LCMS/MS instrument.

Achievements in 2018

PHARMAQUEST

Department of Pharmacology, GMC, Nagpur, had organized the regional level pharmacology quiz, PHARMAQUEST 2018, on 04-09-2018. GMC, Nagpur emerged as the winner, whereas GMC Gondia were the runner-up. Dr. V. M. Motghare, Professor and Head, Department of Pharmacology was the Organizing Chairman and Dr. G.N. Dakhale, Professor, Department of Pharmacology was the Organizing Secretary for the quiz. Five medical colleges from Vidarbha region participated in the quiz. Dr. D. Gosavi and Dr. S. Mahakalkar were available as the judges for the contest. Dr. A. V. Turankar and Dr. Chaitali Chindhalore acted as quiz masters. Dr. A. Niswade, Dean, GMC, Nagpur, was present as the chief guest and handed over the trophies to the winner and runner up team. This quiz was the result of endless efforts of Dr. Paranjape, Dr. Balani, Dr. Sontakke, Dr. Kalikar, Dr. Chakravorty and other faculty. Postgraduate students and the nonteaching staff of Department of Pharmacology, GMC, Nagpur played a vital role in the success of this quiz.

Exams & Results

The department has instituted innovation in teaching like introduction of computer added teaching methods, p drug concept and case based discussion etc. along with age old experimental pharmacology. Various research activities are also going on in the department.

Other

The department has instituted innovation in teaching like introduction of computer added teaching methods, p drug concept and case based discussion etc. along with age old experimental pharmacology. Various research activities are also going on in the department.